Ukungcoliswa kwamasiko amaseli kalula kube inkinga ejwayeleke kakhulu kumalabhorethri e-cell culture, kwesinye isikhathi kubangele imiphumela emibi kakhulu.Ukungcola kwesiko lamaseli kungahlukaniswa izigaba ezimbili, ukungcola kwamakhemikhali njengokungcola okuphakathi, i-serum namanzi, ama-endotoxins, i-plasticiz...
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